The ancient drug salicylate directly activates AMP-activated protein kinase

SA Hawley, MD Fullerton, FA Ross, JD Schertzer… - Science, 2012 - science.org
Salicylate, a plant product, has been in medicinal use since ancient times. More recently, it
has been replaced by synthetic derivatives such as aspirin and salsalate, both of which are …

Goals‐of‐care discussions for adult patients nearing end of life in emergency departments: a systematic review

J Hanning, KJ Walker, D Horrigan… - Emergency Medicine …, 2019 - Wiley Online Library
Goals‐of‐care discussions at end‐of‐life are associated with increased patient satisfaction
and reduced treatment burdens, reduced family and healthcare worker distress and …

Arsenic-induced SUMO-dependent recruitment of RNF4 into PML nuclear bodies

MC Geoffroy, EG Jaffray, KJ Walker… - Molecular biology of the …, 2010 - Am Soc Cell Biol
In acute promyelocytic leukemia (APL), the promyelocytic leukemia (PML) protein is fused to
the retinoic acid receptor alpha (RAR). Arsenic is an effective treatment for this disease as it …

Accuracy of electrocardiogram interpretation improves with emergency medicine training

RJ Hoyle, KJ Walker, G Thomson… - Emergency Medicine …, 2007 - Wiley Online Library
Objective: To assess whether electrocardiogram (ECG) interpretation accuracy improves
with advancing years of emergency medicine training. Methods: A prospective cross …

An economic evaluation of the costs of training a medical scribe to work in Emergency Medicine

KJ Walker, W Dunlop, D Liew, MP Staples… - Emergency Medicine …, 2016 - emj.bmj.com
Objective To undertake a cost analysis of training medical scribes in an ED. Methods This
was a pilot, observational, single-centre study at Cabrini ED, Melbourne, Australia, studying …

[HTML][HTML] The 9-Item Physician Documentation Quality Instrument (PDQI-9) score is not useful in evaluating EMR (scribe) note quality in Emergency Medicine

KJ Walker, A Wang, W Dunlop, H Rodda… - Applied clinical …, 2017 - thieme-connect.com
Background: Scribes are assisting Emergency Physicians by writing their electronic clinical
notes at the bedside during consultations. They increase physician productivity and improve …

Medical scribes in emergency medicine produce financially significant productivity gains for some, but not all emergency physicians

KJ Walker, M Ben‐Meir, D Phillips… - Emergency medicine …, 2016 - Wiley Online Library
Objective The present study aims to determine if a scribe in an Australian ED can assist
emergency physicians to work with increased productivity and to investigate when and …

Timed Up and Go test is not useful as a discharge risk screening tool

KJ Walker, M Bailey, SJ Bradshaw… - Emergency Medicine …, 2006 - Wiley Online Library
Objective: To determine whether the 'Timed Up and Go'(TUG) test is a useful test for
predicting re‐attendance at an ED, emergency hospital admission or death within 90 days in …

Testing a new form to document 'Goals‐of‐Care'discussions regarding plans for end‐of‐life care for patients in an Australian emergency department

AC Mills, M Levinson, WA Dunlop… - Emergency Medicine …, 2018 - Wiley Online Library
Objective There is limited literature to inform the content and format of Goals‐of‐Care forms,
for use by doctors when they are undertaking these important conversations. Methods This …

The repair of 32P decay-damaged phage λ in various radiation-sensitive strains of E. coli K12

BW Glickman, KJ Walker, A Rörsch - Mutation Research/Fundamental and …, 1972 - Elsevier
A number of isogenic radiation-sensitive strains of E. coli K12 were tested for their ability to
reactivate 32 P decay-damaged λ phage. The loss of the Rec, Uvr, Exr and Ror functions …