The extent and analysis of cytokine and cytokine receptor gene polymorphism

LJ Keen - Transplant Immunology, 2002 - Elsevier
Cytokines play an important role in the regulation of normal immune function. In recent years
cytokines and their receptors have been shown to be highly polymorphic. Polymorphisms in …

Monitoring of chimerism following allogeneic haematopoietic stem cell transplantation (HSCT): technical recommendations for the use of short tandem repeat (STR) …

JR Clark, SD Scott, AL Jack, H Lee… - British journal of …, 2015 - Wiley Online Library
Analysis of short tandem repeats (STR) is the predominant method for post‐transplant
monitoring of donor engraftment. It can enable early detection of disease relapse, level of …

Haploidentical stem cell transplantation for children with acute leukaemia

DI Marks, N Khattry, M Cummins… - British journal of …, 2006 - Wiley Online Library
Some children with relapsed or high‐risk acute leukaemia have an improved outcome if they
have an allogeneic stem cell transplant, preferably from a sibling or well‐matched unrelated …

Interleukin-10 and tumor necrosis factor alpha region haplotypes predict transplant-related mortality after unrelated donor stem cell transplantation

LJ Keen, TE DeFor, JL Bidwell, SM Davies, BA Bradley… - Blood, 2004 - ashpublications.org
Certain cytokine gene polymorphisms have been shown to correlate with outcome of human
leukocyte antigen (HLA) identical sibling donor stem cell transplantation (SCT), but in …

Haplotypes in the tumour necrosis factor region and myeloma

GJ Morgan, PJ Adamson, FK Mensah… - British journal of …, 2005 - Wiley Online Library
This study described the haplotypic structure across a region of chromosome 6 including the
tumour necrosis factor (TNF) gene, and investigated its influence on the aetiology of …

Paramedics' experiences of administering fascia iliaca compartment block to patients in South Wales with suspected hip fracture at the scene of injury: results of focus …

BA Evans, A Brown, J Bulger, G Fegan, S Ford… - BMJ open, 2019 - bmjopen.bmj.com
Objectives To explore paramedics' experience of delivering fascia iliaca compartment block
(FICB) to patients with suspected hip fracture at the scene of injury. Design Focus groups …

[HTML][HTML] Rapid Analgesia for Prehospital hip Disruption (RAPID): findings from a randomised feasibility study

JK Jones, BA Evans, G Fegan, S Ford, K Guy… - Pilot and Feasibility …, 2019 - Springer
Background In managing hip fracture, effective pain relief before admission to hospital is
difficult without risking side effects. Although emergency departments routinely use fascia …

Relationship between vascular endothelial growth factor+ 936 genotype and plasma/epithelial lining fluid vascular endothelial growth factor protein levels in patients …

ARL Medford, SIH Godinho, LJ Keen, JL Bidwell… - Chest, 2009 - Elsevier
Background Vascular endothelial growth factor (VEGF) is postulated to have a role in ARDS.
The functional VEGF+ 936 polymorphic T allele is associated with an increased …

Association between non‐Hodgkin lymphoma and haplotypes in the TNF region

CF Spink, LJ Keen, FK Mensah, GR Law… - British journal of …, 2006 - Wiley Online Library
The cytokines tumour necrosis factor‐α (TNFα) and lymphotoxin‐α (LTα) are known to play
key roles in B‐cell growth, differentiation and maturation. Genetic polymorphism within …

Is fascia iliaca compartment block administered by paramedics for suspected hip fracture acceptable to patients? A qualitative study

BA Evans, A Brown, G Fegan, S Ford, K Guy, J Jones… - BMJ open, 2019 - bmjopen.bmj.com
Objective To explore patients' experience of receiving pain relief injection for suspected hip
fracture from paramedics at the location of the injury. Design Qualitative interviews within a …