Outcomes from implementing early goal-directed therapy for severe sepsis and septic shock: a 4-year observational cohort study

N Sivayoham, A Rhodes, T Jaiganesh… - European Journal of …, 2012 - journals.lww.com
Objectives The aim of this study was to determine the outcome of patients with severe sepsis
and septic shock who did and did not receive early goal-directed therapy (EGDT) in the …

Management of severe sepsis and septic shock in the emergency department: a survey of current practice in emergency departments in England

N Sivayoham - Emergency Medicine Journal, 2007 - emj.bmj.com
Aim: To identify the extent to which emergency departments (EDs) in England are involved
in the initiation of the pathway to early goal-directed therapy (EGDT) in patients with severe …

[HTML][HTML] Treatment variables associated with outcome in emergency department patients with suspected sepsis

N Sivayoham, LA Blake, SE Tharimoopantavida… - Annals of Intensive …, 2020 - Springer
Background Early treatment is advocated in the management of patients with suspected
sepsis in the emergency department (ED). We sought to understand the association …

An observational cohort study of the performance of the REDS score compared to the SIRS criteria, NEWS2, CURB65, SOFA, MEDS and PIRO scores to risk-stratify …

N Sivayoham, AN Hussain, L Shabbo… - Annals of …, 2021 - Taylor & Francis
Objective To compare the performance of the Risk-stratification of Emergency Department
suspected Sepsis (REDS) score to the SIRS criteria, NEWS2, CURB65, SOFA, MEDS and …

The MISSED score, a new scoring system to predict Mortality In Severe Sepsis in the Emergency Department: a derivation and validation study

N Sivayoham, A Rhodes, M Cecconi - European Journal of …, 2014 - journals.lww.com
Objective To derive and validate a new scoring system to predict in-hospital mortality in
septic patients in the emergency department (ED). Patients and method Septic patients …

The REDS score: a new scoring system to risk-stratify emergency department suspected sepsis: a derivation and validation study

N Sivayoham, LA Blake, SE Tharimoopantavida… - BMJ open, 2019 - bmjopen.bmj.com
Objective To derive and validate a new clinical prediction rule to risk-stratify emergency
department (ED) patients admitted with suspected sepsis. Design Retrospective prognostic …

[HTML][HTML] Performance of the CURB65, NEWS2, qSOFA, SOFA, REDS, ISARIC 4C, PRIEST and the Novel COVID-19 Severity Scores, Used to Risk-Stratify Emergency …

T Sheerin, P Dwivedi, A Hussain, N Sivayoham - COVID, 2023 - mdpi.com
Objective: To compare the performance of established scoring systems (CURB65, NEWS2,
qSOFA, SOFA and REDS) to the newly developed scores (ISARIC 4C, PRIEST and novel …

[HTML][HTML] Prognostic performance of the REDS score, SOFA score, NEWS2 score, and the red-flag, NICE high-risk, and SIRS criteria to predict survival at 180 days, in …

N Sivayoham, AN Hussain, T Sheerin, P Dwivedi… - Frontiers in …, 2023 - frontiersin.org
Background: Patients admitted to hospital with sepsis are at persistent risk of poor outcome
after discharge. Many tools are available to risk-stratify sepsis patients for in-hospital …

Internal emergency department validation of the simplified MISSED score

N Sivayoham, P Holmes, M Cecconi… - European Journal of …, 2015 - journals.lww.com
Background The MISSED score was derived and validated in emergency department (ED)
patients with sepsis who were admitted to the ICU. This score has now been refined and …

[HTML][HTML] Sensitivity and specificity of monocyte distribution width (MDW) in detecting patients with infection and sepsis in patients on sepsis pathway in the emergency …

M Cusinato, N Sivayoham, T Planche - Infection, 2023 - Springer
Purpose Monocyte distribution width (MDW) is a biomarker for the early identification of
sepsis. We assessed its accuracy in patients presenting with suspected sepsis in the …