MEK1 and MEK2 inhibitors and cancer therapy: the long and winding road
The role of the ERK signalling pathway in cancer is thought to be most prominent in tumours
in which mutations in the receptor tyrosine kinases RAS, BRAF, CRAF, MEK1 or MEK2 drive …
in which mutations in the receptor tyrosine kinases RAS, BRAF, CRAF, MEK1 or MEK2 drive …
Mechanisms of recovery following unilateral labyrinthectomy: a review
PF Smith, IS Curthoys - Brain Research Reviews, 1989 - Elsevier
This paper reviews the literature on the mechanisms responsible for the behavioural
recovery which occurs following unilateral labyrinthectomy (UL). UL causes a syndrome of …
recovery which occurs following unilateral labyrinthectomy (UL). UL causes a syndrome of …
Molecular pathways: fibroblast growth factor signaling: a new therapeutic opportunity in cancer
AN Brooks, E Kilgour, PD Smith - Clinical cancer research, 2012 - AACR
The fibroblast growth factor/fibroblast growth factor receptor (FGF/FGFR) signaling axis plays
an important role in normal organ, vascular, and skeletal development. Deregulation of …
an important role in normal organ, vascular, and skeletal development. Deregulation of …
Laser capture microdissection
MR Emmert-Buck, RF Bonner, PD Smith, RF Chuaqui… - Science, 1996 - science.org
Laser capture microdissection (LCM) under direct microscopic visualization permits rapid
one-step procurement of selected human cell populations from a section of complex …
one-step procurement of selected human cell populations from a section of complex …
[HTML][HTML] DRAM, a p53-induced modulator of autophagy, is critical for apoptosis
D Crighton, S Wilkinson, J O'Prey, N Syed, P Smith… - Cell, 2006 - cell.com
Inactivation of cell death is a major step in tumor development, and p53, a tumor suppressor
frequently mutated in cancer, is a critical mediator of cell death. While a role for p53 in …
frequently mutated in cancer, is a critical mediator of cell death. While a role for p53 in …
Reverberation measurements for 17 quasars and the size-mass-luminosity relations in active galactic nuclei
Correlated variations in the line and continuum emission from active galactic nuclei (AGNs)
can be used to determine the size and geometry of the broad emission-line regions (BLRs) …
can be used to determine the size and geometry of the broad emission-line regions (BLRs) …
[BOOK][B] Marketing communications: an integrated approach
PR Smith, J Taylor - 2004 - books.google.com
Marketing Communications rapidly established itself as an international best-seller and has
been listed as a" marketing classic" by the Marketing Society and as a" marketing major" by …
been listed as a" marketing classic" by the Marketing Society and as a" marketing major" by …
Decline of the North American avifauna
Species extinctions have defined the global biodiversity crisis, but extinction begins with loss
in abundance of individuals that can result in compositional and functional changes of …
in abundance of individuals that can result in compositional and functional changes of …
[BOOK][B] eMarketing eXcellence: Planning and optimizing your digital marketing
D Chaffey, PR Smith - 2013 - taylorfrancis.com
Now in its fourth edition, the hugely successful Emarketing Excellence is fully updated;
keeping you in line with the changes in this dynamic and exciting field and helping you …
keeping you in line with the changes in this dynamic and exciting field and helping you …
Follicular lymphoma international prognostic index
P Solal-Céligny, P Roy, P Colombat, J White… - Blood, 2004 - ashpublications.org
The prognosis of follicular lymphomas (FL) is heterogeneous and numerous treatments may
be proposed. A validated prognostic index (PI) would help in evaluating and choosing these …
be proposed. A validated prognostic index (PI) would help in evaluating and choosing these …