Post-stroke dysphagia: a review and design considerations for future trials

DL Cohen, C Roffe, J Beavan… - … Journal of Stroke, 2016 - journals.sagepub.com
Post-stroke dysphagia (a difficulty in swallowing after a stroke) is a common and expensive
complication of acute stroke and is associated with increased mortality, morbidity, and …

Tackling challenges in care of Alzheimer's disease and other dementias amid the COVID‐19 pandemic, now and in the future

VCT Mok, S Pendlebury, A Wong, S Alladi… - Alzheimer's & …, 2020 - Wiley Online Library
We have provided an overview on the profound impact of COVID‐19 upon older people with
Alzheimer's disease and other dementias and the challenges encountered in our …

Pharmacological treatment and prevention of cerebral small vessel disease: a review of potential interventions

PM Bath, JM Wardlaw - International Journal of Stroke, 2015 - journals.sagepub.com
Small vessel disease encompasses lacunar stroke, white matter hyperintensities, lacunes
and microbleeds. It causes a quarter of all ischemic strokes, is the commonest cause of …

Vascular dysfunction—the disregarded partner of Alzheimer's disease

MD Sweeney, A Montagne, AP Sagare, DA Nation… - Alzheimer's & …, 2019 - Elsevier
Increasing evidence recognizes Alzheimer's disease (AD) as a multifactorial and
heterogeneous disease with multiple contributors to its pathophysiology, including vascular …

[HTML][HTML] Ticagrelor versus Clopidogrel in CYP2C19 Loss-of-Function Carriers with Stroke or TIA

Y Wang, X Meng, A Wang, X Xie, Y Pan… - … England Journal of …, 2021 - Mass Medical Soc
Background Comparisons between ticagrelor and clopidogrel for the secondary prevention
of stroke in CYP2C19 loss-of-function carriers have not been extensively performed …

[HTML][HTML] Low-dose versus standard-dose intravenous alteplase in acute ischemic stroke

CS Anderson, T Robinson, RI Lindley… - … England Journal of …, 2016 - Mass Medical Soc
Background Thrombolytic therapy for acute ischemic stroke with a lower-than-standard dose
of intravenous alteplase may improve recovery along with a reduced risk of intracerebral …

Action plan for stroke in Europe 2018–2030

B Norrving, J Barrick, A Davalos… - European stroke …, 2018 - journals.sagepub.com
Two previous pan-European consensus meetings, the 1995 and 2006 Helsingborg
meetings, were convened to review the scientific evidence and the state of current services …

[HTML][HTML] Tranexamic acid for hyperacute primary IntraCerebral Haemorrhage (TICH-2): an international randomised, placebo-controlled, phase 3 superiority trial

N Sprigg, K Flaherty, JP Appleton, RAS Salman… - The Lancet, 2018 - thelancet.com
Background Tranexamic acid can prevent death due to bleeding after trauma and post-
partum haemorrhage. We aimed to assess whether tranexamic acid reduces haematoma …

Human neural stem cells in patients with chronic ischaemic stroke (PISCES): a phase 1, first-in-man study

D Kalladka, J Sinden, K Pollock, C Haig, J McLean… - The Lancet, 2016 - thelancet.com
Background CTX0E03 is an immortalised human neural stem-cell line from which a drug
product (CTX-DP) was developed for allogeneic therapy. Dose-dependent improvement in …

Intensive blood pressure reduction with intravenous thrombolysis therapy for acute ischaemic stroke (ENCHANTED): an international, randomised, open-label …

CS Anderson, Y Huang, RI Lindley, X Chen, H Arima… - The Lancet, 2019 - thelancet.com
Background Systolic blood pressure of more than 185 mm Hg is a contraindication to
thrombolytic treatment with intravenous alteplase in patients with acute ischaemic stroke, but …