Structure and development of single domain antibodies as modules for therapeutics and diagnostics
Since their discovery just over 25 years ago, the single variable domain from heavy-chain-
only antibodies plays a role in an increasing number of antibody-based applications …
only antibodies plays a role in an increasing number of antibody-based applications …
Teaching an old scaffold new tricks: monobodies constructed using alternative surfaces of the FN3 scaffold
A Koide, J Wojcik, RN Gilbreth, RJ Hoey… - Journal of molecular …, 2012 - Elsevier
The fibronectin type III domain (FN3) has become one of the most widely used non-antibody
scaffolds for generating new binding proteins. Because of its structural homology to the …
scaffolds for generating new binding proteins. Because of its structural homology to the …
Online and Blended Learning: A Survey of Policy and Practice from K-12 Schools around the World.
In 2006, the North American Council for Online Learning (NACOL) conducted its first
international survey, researching how other countries were implementing online and …
international survey, researching how other countries were implementing online and …
[HTML][HTML] A high through-put platform for recombinant antibodies to folded proteins
Antibodies are key reagents in biology and medicine, but commercial sources are rarely
recombinant and thus do not provide a permanent and renewable resource. Here, we …
recombinant and thus do not provide a permanent and renewable resource. Here, we …
Conformational states and recognition of amyloidogenic peptides of human insulin-degrading enzyme
LA McCord, WG Liang, E Dowdell… - Proceedings of the …, 2013 - National Acad Sciences
Insulin-degrading enzyme (IDE) selectively degrades the monomer of amyloidogenic
peptides and contributes to clearance of amyloid β (Aβ). Thus, IDE retards the progression of …
peptides and contributes to clearance of amyloid β (Aβ). Thus, IDE retards the progression of …
Coexpression of parathyroid hormone related protein and its receptor in early breast cancer predicts poor patient survival
R Linforth, N Anderson, R Hoey, T Nolan, S Downey… - Clinical cancer …, 2002 - AACR
Purpose: Parathyroid hormone-related protein (PTHRP) is in part responsible for the clinical
syndrome of hypercalcaemia of malignancy and has been implicated as an important factor …
syndrome of hypercalcaemia of malignancy and has been implicated as an important factor …
Examining the characteristics and content of instructor discussion interaction upon student outcomes in an online course.
R Hoey - Online Learning, 2017 - ERIC
Teaching presence facilitates students' social and cognitive presence in online courses.
Instructor interaction in discussion forums, a widely adopted instructional strategy …
Instructor interaction in discussion forums, a widely adopted instructional strategy …
[HTML][HTML] The parathyroid hormone-related protein receptor is expressed in breast cancer bone metastases and promotes autocrine proliferation in breast carcinoma …
RP Hoey, C Sanderson, J Iddon, G Brady… - British journal of …, 2003 - nature.com
Overproduction of parathyroid hormone-related protein (PTHRP) occurs in a high proportion
of primary breast cancers (PBC) and is strongly implicated in their metastatic spread to bone …
of primary breast cancers (PBC) and is strongly implicated in their metastatic spread to bone …
The effects of dietary fat content on performance and body composition of farmed rainbow trout (Oncorhynchus mykiss)
…, R Foy, D Rice, J McKendry, RJ Mairs, R Hoey - Aquaculture, 1997 - Elsevier
Three studies were conducted, one in autumn with decreasing water temperatures (11° to 5°
C), one in spring with rising temperatures (7° to 12° C) and one in summer in relatively …
C), one in spring with rising temperatures (7° to 12° C) and one in summer in relatively …
Applications for an engineered Protein-G variant with a pH controllable affinity to antibody fragments
LJ Bailey, KM Sheehy, RJ Hoey, ZP Schaefer… - Journal of …, 2014 - Elsevier
Immunoglobulin binding proteins (IBPs) are broadly used as reagents for the purification
and detection of antibodies. Among the IBPs, the most widely used are Protein-A and …
and detection of antibodies. Among the IBPs, the most widely used are Protein-A and …