User profiles for "author:R Jenner"
 | Richard JennerProfessor of Molecular Biology, University College London Verified email at ucl.ac.uk Cited by 15646 |
Insights into host responses against pathogens from transcriptional profiling
DNA microarrays have allowed us to monitor the effects of pathogens on host-cell gene
expression programmes in great depth and on a broad scale. The comparison of results that …
expression programmes in great depth and on a broad scale. The comparison of results that …
Effects of CPAP on body weight in patients with obstructive sleep apnoea: a meta-analysis of randomised trials
Introduction The impact of obstructive sleep apnoea (OSA) treatment with CPAP on weight is
not clear. This meta-analysis was designed to assess whether OSA treatment with CPAP …
not clear. This meta-analysis was designed to assess whether OSA treatment with CPAP …
[HTML][HTML] The diversity of venom: the importance of behavior and venom system morphology in understanding its ecology and evolution
Venoms are one of the most convergent of animal traits known, and encompass a much
greater taxonomic and functional diversity than is commonly appreciated. This knowledge …
greater taxonomic and functional diversity than is commonly appreciated. This knowledge …
[HTML][HTML] Core transcriptional regulatory circuitry in human embryonic stem cells
The transcription factors OCT4, SOX2, and NANOG have essential roles in early
development and are required for the propagation of undifferentiated embryonic stem (ES) …
development and are required for the propagation of undifferentiated embryonic stem (ES) …
[HTML][HTML] Control of developmental regulators by Polycomb in human embryonic stem cells
Polycomb group proteins are essential for early development in metazoans, but their
contributions to human development are not well understood. We have mapped the …
contributions to human development are not well understood. We have mapped the …
Genome-wide analysis of cAMP-response element binding protein occupancy, phosphorylation, and target gene activation in human tissues
…, J Best, H Chen, R Jenner… - Proceedings of the …, 2005 - National Acad Sciences
Hormones and nutrients often induce genetic programs via signaling pathways that interface
with gene-specific activators. Activation of the cAMP pathway, for example, stimulates …
with gene-specific activators. Activation of the cAMP pathway, for example, stimulates …
[PDF][PDF] Short RNAs are transcribed from repressed polycomb target genes and interact with polycomb repressive complex-2
Polycomb proteins maintain cell identity by repressing the expression of developmental
regulators specific for other cell types. Polycomb repressive complex-2 (PRC2) catalyzes …
regulators specific for other cell types. Polycomb repressive complex-2 (PRC2) catalyzes …
[HTML][HTML] HIV-1 capsid-cyclophilin interactions determine nuclear import pathway, integration targeting and replication efficiency
T Schaller, KE Ocwieja, J Rasaiyaah, AJ Price… - PLoS …, 2011 - journals.plos.org
Lentiviruses such as HIV-1 traverse nuclear pore complexes (NPC) and infect terminally
differentiated non-dividing cells, but how they do this is unclear. The cytoplasmic NPC …
differentiated non-dividing cells, but how they do this is unclear. The cytoplasmic NPC …
Global and Hox-specific roles for the MLL1 methyltransferase
MG Guenther, RG Jenner, B Chevalier… - Proceedings of the …, 2005 - National Acad Sciences
The mixed-lineage leukemia (MLL1/ALL-1/HRX) histone methyltransferase is involved in the
epigenetic maintenance of transcriptional memory and the pathogenesis of human …
epigenetic maintenance of transcriptional memory and the pathogenesis of human …
Kaposi's sarcoma-associated herpesvirus latent and lytic gene expression as revealed by DNA arrays
Kaposi's sarcoma-associated herpesvirus (KSHV; human herpesvirus 8) is associated with
three human tumors, Kaposi's sarcoma, primary effusion lymphoma (PEL), and multicentric …
three human tumors, Kaposi's sarcoma, primary effusion lymphoma (PEL), and multicentric …