[HTML][HTML] The mental health impact of the covid-19 pandemic on healthcare workers, and interventions to help them: A rapid systematic review

AE Muller, EV Hafstad, JPW Himmels, G Smedslund… - Psychiatry …, 2020 - Elsevier
The covid-19 pandemic has heavily burdened healthcare systems throughout the world. We
performed a rapid systematic review to identify, assess and summarize research on the …

[HTML][HTML] Factors affecting mental health of health care workers during coronavirus disease outbreaks (SARS, MERS & COVID-19): A rapid systematic review

N De Brier, S Stroobants, P Vandekerckhove… - PloS one, 2020 - journals.plos.org
Introduction The novel Coronavirus Disease (COVID-19) outbreak currently puts health care
workers at high risk of both physical and mental health problems. This study aimed to …

[HTML][HTML] rAAV2/7 vector-mediated overexpression of alpha-synuclein in mouse substantia nigra induces protein aggregation and progressive dose-dependent …

M Oliveras-Salvá, A Van der Perren, N Casadei… - Molecular …, 2013 - Springer
Background Alpha-synuclein is a key protein implicated in the pathogenesis of Parkinson's
disease (PD). It is the main component of the Lewy bodies, a cardinal neuropathological …

Postnatal disruption of the disintegrin/metalloproteinase ADAM10 in brain causes epileptic seizures, learning deficits, altered spine morphology, and defective …

J Prox, C Bernreuther, H Altmeppen… - Journal of …, 2013 - Soc Neuroscience
The metalloproteinase ADAM10 is of importance for Notch-dependent cortical brain
development. The protease is tightly linked with α-secretase activity toward the amyloid …

Arylsulfatase G inactivation causes loss of heparan sulfate 3-O-sulfatase activity and mucopolysaccharidosis in mice

B Kowalewski, WC Lamanna… - Proceedings of the …, 2012 - National Acad Sciences
Deficiency of glycosaminoglycan (GAG) degradation causes a subclass of lysosomal
storage disorders called mucopolysaccharidoses (MPSs), many of which present with …

[HTML][HTML] LAMP-2 deficiency leads to hippocampal dysfunction but normal clearance of neuronal substrates of chaperone-mediated autophagy in a mouse model for …

M Rothaug, S Stroobants, M Schweizer… - Acta neuropathologica …, 2015 - Springer
Abstract The Lysosomal Associated Membrane Protein type-2 (LAMP-2) is an abundant
lysosomal membrane protein with an important role in immunity, macroautophagy (MA) and …

Brain endothelial TAK1 and NEMO safeguard the neurovascular unit

DA Ridder, J Wenzel, K Müller, K Töllner… - Journal of Experimental …, 2015 - rupress.org
Inactivating mutations of the NF-κB essential modulator (NEMO), a key component of NF-κB
signaling, cause the genetic disease incontinentia pigmenti (IP). This leads to severe …

Intracerebroventricular enzyme infusion corrects central nervous system pathology and dysfunction in a mouse model of metachromatic leukodystrophy

S Stroobants, D Gerlach, F Matthes… - Human molecular …, 2011 - academic.oup.com
Arylsulfatase A (ASA) catalyzes the desulfation of sulfatide, a major lipid component of
myelin. Inherited functional deficiencies of ASA cause the lysosomal storage disease (LSD) …

Matrix-binding vascular endothelial growth factor (VEGF) isoforms guide granule cell migration in the cerebellum via VEGF receptor Flk1

CR De Almodovar, C Coulon, PA Salin… - Journal of …, 2010 - Soc Neuroscience
Vascular endothelial growth factor (VEGF) regulates angiogenesis, but also has important,
yet poorly characterized roles in neuronal wiring. Using several genetic and in vitro …

Deficits in acquisition and extinction of conditioned responses in mGluR7 knockout mice

H Goddyn, Z Callaerts-Vegh, S Stroobants… - Neurobiology of learning …, 2008 - Elsevier
Metabotropic glutamate receptor 7 (mGluR7) is expressed in brain regions implicated in
emotional learning and working memory, and previous behavioral experiments indicated …