[HTML][HTML] Changing landscape in the treatment of adult acute lymphoblastic leukemia (ALL)

T Künz, AW Hauswirth, G Hetzenauer, J Rudzki… - Cancers, 2022 - mdpi.com
Simple Summary The improved understanding of acute lymphoblastic leukemia has brought
with it several new therapy strategies as well as novel treatment agents. The aim of our …

The selective cyclooxygenase‐2 inhibitor rofecoxib reduces kainate‐induced cell death in the rat hippocampus

T Kunz, EH Oliw - European Journal of Neuroscience, 2001 - Wiley Online Library
Abstract Treatment of male Sprague–Dawley rats with kainic acid (10 mg/kg, ip) triggered
limbic seizures in 60% of the animals starting within 30 min and lasting for about 6 h …

Cytochromes P450 with bisallylic hydroxylation activity on arachidonic and linoleic acids studied with human recombinant enzymes and with human and rat liver …

J Bylund, T Kunz, K Valmsen, EH Oliw - Journal of Pharmacology and …, 1998 - ASPET
Bisallylic carbons of polyunsaturated fatty acids can be hydroxylated in NADPH-dependent
reactions in liver microsomes. Human recombinant cytochromes P450 and human and rat …

Cyclooxygenase-2, Prostaglandin Synthases, and Prostaglandin H2 Metabolism in Traumatic Brain Injury in the Rat

T Kunz, N Marklund, L Hillered, EH Oliw - Journal of neurotrauma, 2002 - liebertpub.com
Inflammatory mediators are important in traumatic brain injury (TBI). The objective of the
present study was to investigate the expression of cyclooxygenase-2 (COX-2), prostaglandin …

[HTML][HTML] The agony of choice—where to place the wave of BCMA-targeted therapies in the multiple myeloma treatment puzzle in 2022 and beyond

I Strassl, M Schreder, N Steiner, J Rudzki, H Agis… - Cancers, 2021 - mdpi.com
Simple Summary There is no doubt that immunotherapeutic approaches will change the
current treatment landscape of multiple myeloma in the near future; in particular, a wave of …

Nimesulide aggravates kainic acid‐induced seizures in the rat

T Kunz, EH Oliw - Pharmacology & toxicology, 2001 - Wiley Online Library
Treatment of rats with kainic acid (10 mg/kg, intraperitoneally) triggers limbic seizures.
Cyclooxygenase‐2 mRNA is expressed in the hippocampus and cortex after 8 hr and …

[HTML][HTML] Poor mobilizers in lymphoma but not myeloma patients had significantly poorer progression-free survival after autologous stem cell transplantation: results of …

N Steiner, G Göbel, L Mauser, L Mühlnikel… - Cancers, 2023 - mdpi.com
Simple Summary Herein, we retrospectively analyze in our single-center study real-life data
of 357 myeloma and lymphoma patients mobilized with granulocyte colony-stimulating factor …

Effects of the selective cyclooxygenase-2 inhibitor rofecoxib on cell death following traumatic brain injury in the rat

T Kunz, N Marklund, L Hillered… - Restorative neurology …, 2006 - content.iospress.com
Purpose: Lateral fluid percussion brain injury (FPI) increases cyclooxygenase-2 (COX-2)
expression in the cortex and hippocampus. The objective was to investigate whether the …

[HTML][HTML] VuWiki: An ontology-based semantic wiki for vulnerability assessments

B Khazai, T Kunz-Plapp, C Büscher… - International Journal of …, 2014 - Springer
Three decades of vulnerability research have generated a complex and growing body of
knowledge. The concept of vulnerability, as well as its implementation in vulnerability …

[HTML][HTML] Tailoring climate parameters to information needs for local adaptation to climate change

J Hackenbruch, T Kunz-Plapp, S Müller, JW Schipper - Climate, 2017 - mdpi.com
Municipalities are important actors in the field of local climate change adaptation.
Stakeholders need scientifically sound information tailored to their needs to make local …